SOLIRIS

This brand name is authorized in Austria, Australia, Brazil, Canada, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States

Active ingredients

The drug SOLIRIS contains one active pharmaceutical ingredient (API):

1 Eculizumab UNII A3ULP0F556 - ECULIZUMAB

Eculizumab is a monoclonal antibody, a terminal complement inhibitor that specifically binds to the complement protein C5 with high affinity, thereby inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9. Eculizumab preserves the early components of complement activation that are essential for opsonization of microorganisms and clearance of immune complexes. Read about Eculizumab

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
SOLIRIS Concentrate for solution for infusion	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AJ01	Eculizumab	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AJ Complement inhibitors
Discover more medicines within L04AJ01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10182X, 10183Y, 10190H, 10191J, 10192K, 10194M, 10521R, 10525Y
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 565517100000001
Country: CA	Health Products and Food Branch	Identifier(s): 02322285
Country: EE	Ravimiamet	Identifier(s): 1342011
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 07393001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 102268
Country: FR	Base de données publique des médicaments	Identifier(s): 61969188
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 118126
Country: HK	Department of Health Drug Office	Identifier(s): 61188
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 6725
Country: IT	Agenzia del Farmaco	Identifier(s): 038083010
Country: JP	医薬品医療機器総合機構	Identifier(s): 6399424A1023
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1030813
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 14812
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100192746
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W68259001
Country: SG	Health Sciences Authority	Identifier(s): 14226P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8680131470013
Country: US	FDA, National Drug Code	Identifier(s): 25682-001