This brand name is authorized in Austria, Brazil, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States
The drug SYLVANT contains one active pharmaceutical ingredient (API):
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1
Siltuximab
UNII T4H8FMA7IM - SILTUXIMAB
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Siltuximab is a monoclonal antibody that forms high affinity, stable complexes with soluble bioactive forms of human IL-6. Siltuximab prevents the binding of human IL-6 to both soluble and membrane-bound IL-6 receptors (IL-6R), thus inhibiting the formation of the hexameric signaling complex with gp130 on the cell surface. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| SYLVANT Powder for concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L04AC11 | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 514515080027701, 514515080027801 |
| Country: CA | Health Products and Food Branch | Identifier(s): 02435128, 02435136 |
| Country: EE | Ravimiamet | Identifier(s): 1649189, 1649190 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 114928001 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 161783 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 60622302, 63846800 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 247966, 247977 |
| Country: HK | Department of Health Drug Office | Identifier(s): 64495, 64496 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 7796, 7797 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 043447010, 043447022 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1073468, 1073469 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 117099, 117102 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 17150, 17151 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100317716, 100317722 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W66521001, W66522001 |
| Country: SG | Health Sciences Authority | Identifier(s): 14762P, 14763P |
| Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8680885579178, 8680885579185 |
| Country: US | FDA, National Drug Code | Identifier(s): 57894-420, 57894-421, 73090-420, 73090-421 |
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