TALZENNA

This brand name is authorized in United States. It is also authorized in Austria, Croatia, Ecuador, Estonia, France, Hong Kong SAR China, Ireland, Israel, Italy, Lithuania, Netherlands, Nigeria, Poland, Romania, Turkey, UK.

Active ingredients

The drug TALZENNA contains one active pharmaceutical ingredient (API):

1	Talazoparib UNII 02WK9U5NZC - TALAZOPARIB TOSYLATE
	Talazoparib is an inhibitor of PARP enzymes, PARP1, and PARP2. PARP enzymes are involved in cellular DNA damage response signalling pathways such as DNA repair, gene transcription, and cell death. PARP inhibitors (PARPi) exert cytotoxic effects on cancer cells by 2 mechanisms, inhibition of PARP catalytic activity and by PARP trapping, whereby PARP protein bound to a PARPi does not readily dissociate from a DNA lesion, thus preventing DNA repair, replication, and transcription, thereby resulting in apoptosis and/or cell death.
	Read more about Talazoparib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
TALZENNA Hard capsule	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01XK04		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
Discover more medicines within L01XK04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	6233-MEE-0521, 6553-MEE-0821
EE	Ravimiamet	1798623, 1798634, 1798645, 1798656
FR	Base de données publique des médicaments	61710730, 62184233, 65301389
GB	Medicines & Healthcare Products Regulatory Agency	376499, 376508
HK	Department of Health Drug Office	66589, 66590
IE	Health Products Regulatory Authority	89076, 89077
IL	מִשְׂרַד הַבְּרִיאוּת	8544, 8545
IT	Agenzia del Farmaco	048057018, 048057020, 048057032, 048057044, 048057057, 048057069
LT	Valstybinė vaistų kontrolės tarnyba	1088121, 1088122, 1088123, 1088124, 1088125, 1088126
NG	Registered Drug Product Database	A4-100089, A4-100090
Switch country to Nigeria in order to find specific presentations of TALZENNA
NL	Z-Index G-Standaard, PRK	201820, 201839
PL	Rejestru Produktów Leczniczych	100423387, 100423393
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W66678001, W66678002, W66678003, W66678004, W66679001, W66679002
TR	İlaç ve Tıbbi Cihaz Kurumu	8681308151100, 8681308151117
US	FDA, National Drug Code	0069-0296, 0069-1195, 63539-295