TARGRETIN

This brand name is authorized in Austria, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States

Active ingredients

The drug TARGRETIN contains one active pharmaceutical ingredient (API):

1 Bexarotene UNII A61RXM4375 - BEXAROTENE

Bexarotene is a synthetic compound that exerts its biological action through selective binding and activation of the three RXRs: α, β, and γ. Once activated, these receptors function as transcription factors that regulate processes such as cellular differentiation and proliferation, apoptosis, and insulin sensitisation. The exact mechanism of action of bexarotene in the treatment of cutaneous T-cell lymphoma (CTCL) is unknown. Read about Bexarotene

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
TARGRETIN Soft capsule	European Medicines Agency (EU)	MPI, EU: SmPC
Targretin Capsules	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01XF03	Bexarotene	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XF Retinoids for cancer treatment
Discover more medicines within L01XF03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1196984
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 01178001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 431604
Country: FR	Base de données publique des médicaments	Identifier(s): 69197468
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 43294
Country: IE	Health Products Regulatory Authority	Identifier(s): 88403
Country: IT	Agenzia del Farmaco	Identifier(s): 035710019
Country: JP	医薬品医療機器総合機構	Identifier(s): 4291042M1022
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1031005
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 70610
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100133583
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W66654001
Country: US	FDA, National Drug Code	Identifier(s): 0187-5525, 0187-5526