This brand name is authorized in Austria, Brazil, Cyprus, Estonia, Spain, France, Croatia, Ireland, Italy, Lithuania, Netherlands, New Zealand, Poland, Turkey, United Kingdom, United States, South Africa
The drug TASMAR contains one active pharmaceutical ingredient (API):
1
Tolcapone
UNII CIF6334OLY - TOLCAPONE
|
Tolcapone is an orally active, selective and reversible catechol-O-methyltransferase (COMT) inhibitor. Administered concomitantly with levodopa and an aromatic amino acid decarboxylase inhibitor (AADC-I), it leads to more stable plasma levels of levodopa by reducing metabolism of levodopa to 3-methoxy-4-hydroxy-L-phenylalanine (3-OMD). High levels of plasma 3-OMD have been associated with poor response to levodopa in Parkinson’s disease patients. |
Below package inserts are available for further reading:
Title | Information Source | Document Type | |
---|---|---|---|
TASMAR Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
N04BX01 | Tolcapone | N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BX Other dopaminergic agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 512003001119311 |
Country: EE | Ravimiamet | Identifier(s): 1196928, 1196939, 1196940, 1196951, 1196962, 1196973, 1598496 |
Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 97044003 |
Country: FR | Base de données publique des médicaments | Identifier(s): 67077388 |
Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 90611 |
Country: IE | Health Products Regulatory Authority | Identifier(s): 49675 |
Country: IT | Agenzia del Farmaco | Identifier(s): 033280025, 033280037, 033280049, 033280064, 033280076, 033280088, 033280090, 033280102, 033280114 |
Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1031010, 1031011, 1031012, 1031013, 1031014, 1031015, 1031016, 1031017, 1081084 |
Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 80179 |
Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 7360 |
Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100083537, 100085097 |
Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8698856090010 |
Country: US | FDA, National Drug Code | Identifier(s): 0187-0938 |
Country: ZA | Health Products Regulatory Authority | Identifier(s): 31/5.4.1/0396 |
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