TEPMETKO

This brand name is authorized in Austria, Brazil, Estonia, Finland, Croatia, Israel, Italy, Japan, Lithuania, Poland, United States

Active ingredients

The drug TEPMETKO contains one active pharmaceutical ingredient (API):

1 Tepotinib UNII VY5YX2TQ1F - TEPOTINIB HYDROCHLORIDE

Tepotinib is a reversible Type I adenosine triphosphate (ATP)-competitive small molecule inhibitor of MET. Tepotinib blocked MET phosphorylation and MET-dependent downstream signalling in a dose-dependent manner. Tepotinib demonstrated pronounced anti-tumour activity in tumours with oncogenic activation of MET, such as METex14 skipping alterations. Read about Tepotinib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
TEPMETKO Film-coated tablet	FDA, National Drug Code (US)	MPI, US: SPL/PLR
TEPMETKO Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EX21		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EX Other protein kinase inhibitors
Discover more medicines within L01EX21

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 525421090053002
Country: EE	Ravimiamet	Identifier(s): 1876293
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 176387
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 9037
Country: IT	Agenzia del Farmaco	Identifier(s): 049967019
Country: JP	医薬品医療機器総合機構	Identifier(s): 4291065F1024
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1094284
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100466998
Country: US	FDA, National Drug Code	Identifier(s): 44087-5000