TEZSPIRE

This brand name is authorized in United States. It is also authorized in Austria, Canada, Croatia, Estonia, France, Ireland, Israel, Italy, Japan, Lithuania, Romania, Spain, UK.

Active ingredients

The drug TEZSPIRE contains one active pharmaceutical ingredient (API):

1	Tezepelumab UNII RJ1IW3B4QX - TEZEPELUMAB
	Tezepelumab is a monoclonal antibody (IgG2λ) directed against thymic stromal lymphopoietin (TSLP), preventing its interaction with the heterodimeric TSLP receptor. In asthma, both allergic and non-allergic triggers induce TSLP production. Blocking TSLP with tezepelumab reduces a broad spectrum of biomarkers and cytokines associated with airway inflammation; however, the mechanism of action of tezepelumab in asthma has not been definitively established.
	Read more about Tezepelumab

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
TEZSPIRE Solution for injection	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
R03DX11		R Respiratory system → R03 Drugs for obstructive airway diseases → R03D Other systemic drugs for obstructive airway diseases → R03DX Other systemic drugs for obstructive airway diseases
Discover more medicines within R03DX11

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
CA	Health Products and Food Branch	02529548, 02529556
EE	Ravimiamet	1889949, 3053528, 3053539, 3053540
ES	Centro de información online de medicamentos de la AEMPS	1221677001, 1221677003
FR	Base de données publique des médicaments	68954908, 69714595
IL	מִשְׂרַד הַבְּרִיאוּת	9255
IT	Agenzia del Farmaco	050354012, 050354024, 050354036, 050354048
JP	医薬品医療機器総合機構	2290403G1025
LT	Valstybinė vaistų kontrolės tarnyba	1095625, 1095953, 1096532, 1097001
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W69162001, W69476001
US	FDA, National Drug Code	55513-100, 55513-112