TOFRANIL

This brand name is authorized in United States. It is also authorized in Australia, Brazil, France, Japan, Mexico, New Zealand, Spain, Turkey.

Active ingredients

The drug TOFRANIL contains one active pharmaceutical ingredient (API):

1	Imipramine UNII BKE5Q1J60U - IMIPRAMINE HYDROCHLORIDE
	Imipramine is a tricyclic antidepressant and has several pharmacological actions including alpha-adrenolytic, antihistamine, anticholinergic and 5HT-receptor blocking properties. However, the main therapeutic activity is believed to be inhibition of the neuronal re-uptake of noradrenaline and 5HT. Imipramine is a so-called “mixed” re-uptake blocker, i.e. it inhibits the reuptake of NA and 5HT to about the same extent.
	Read more about Imipramine

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
TOFRANIL Sugar-coated tablet	MPI, US: SPL/Old	FDA, National Drug Code (US)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
N06AA02	Imipramine	N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AA Non-selective monoamine reuptake inhibitors
Discover more medicines within N06AA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	2420J, 2421K
BR	Câmara de Regulação do Mercado de Medicamentos	505615110041117, 505615110041217, 526527903111318, 526527904118316
ES	Centro de información online de medicamentos de la AEMPS	31004, 40366, 48384
FR	Base de données publique des médicaments	67117128, 68574699
JP	医薬品医療機器総合機構	1174006F1078, 1174006F2074
MX	Comisión Federal para la Protección contra Riesgos Sanitarios	53089
NZ	Medicines and Medical Devices Safety Authority	10014, 10015
TR	İlaç ve Tıbbi Cihaz Kurumu	8699708121517, 8699708121524
US	FDA, National Drug Code	0406-9920, 0406-9921, 0406-9922