This brand name is authorized in Australia, New Zealand
The drug TRAJENTAMET contains a combination of these active pharmaceutical ingredients (APIs):
1
Linagliptin
UNII 3X29ZEJ4R2 - LINAGLIPTIN
|
Linagliptin is an inhibitor of the enzyme DPP-4 (dipeptidyl peptidase 4, EC 3.4.14.5) an enzyme which is involved in the inactivation of the incretin hormones GLP-1 and GIP (glucagon-like peptide1, glucose-dependent insulinotropic polypeptide). These hormones are rapidly degraded by the enzyme DPP-4. Both incretin hormones are involved in the physiological regulation of glucose homeostasis. |
2
Metformin
UNII 786Z46389E - METFORMIN HYDROCHLORIDE
|
Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
A10BD11 | Metformin and linagliptin | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BD Combinations of oral blood glucose lowering drugs |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 10038H, 10044P, 10045Q, 11274J, 11282T, 11294K |
Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 17367, 17368, 17369 |
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