This brand name is authorized in Austria, Australia, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States
The drug TRIZIVIR contains a combination of these active pharmaceutical ingredients (APIs):
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1
Abacavir
UNII J220T4J9Q2 - ABACAVIR SULFATE
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Abacavir is a NRTI. It is a potent selective inhibitor of HIV-1 and HIV-2. Abacavir is metabolised intracellularly to the active moiety, carbovir 5'-triphosphate (TP). In vitro studies have demonstrated that its mechanism of action in relation to HIV is inhibition of the HIV reverse transcriptase enzyme, an event which results in chain termination and interruption of the viral replication cycle. |
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2
Lamivudine
UNII 2T8Q726O95 - LAMIVUDINE
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Lamivudine is a nucleoside analogue which has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Its main mode of action is as a chain terminator of viral reverse transcription. |
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3
Zidovudine
UNII 4B9XT59T7S - ZIDOVUDINE
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Zidovudine is an antiviral agent which is highly active in vitro against retroviruses including the Human Immunodeficiency Virus (HIV). |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| TRIZIVIR Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J05AR04 | Zidovudine, lamivudine and abacavir | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AR Antivirals for treatment of HIV infections, combinations |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 10305J |
| Country: EE | Ravimiamet | Identifier(s): 1110980 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 100156004 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 435748 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 64976070 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 44192 |
| Country: HK | Department of Health Drug Office | Identifier(s): 49277 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 034947010, 034947022, 034947034, 034947046 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1007906, 1031458, 1055422, 1056594 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 136026 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100110487 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W65016001, W65016002 |
| Country: US | FDA, National Drug Code | Identifier(s): 49702-217 |
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