This brand name is authorized in Spain, France, Malta, Romania
The drug TWICOR contains a combination of these active pharmaceutical ingredients (APIs):
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1
Rosuvastatin
UNII 83MVU38M7Q - ROSUVASTATIN CALCIUM
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Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles. |
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2
Ezetimibe
UNII EOR26LQQ24 - EZETIMIBE
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Ezetimibe is in a new class of lipid-lowering compounds that selectively inhibit the intestinal absorption of cholesterol. The molecular target of ezetimibe is the sterol transporter, Niemann-Pick C1-Like 1 (NPC1L1), which is responsible for the intestinal uptake of cholesterol. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| TWICOR Film-coated tablet | Medicines Authority (MT) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10BA06 | C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BA Combinations of various lipid modifying agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 82426, 83660 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 64518219, 64605955 |
| Country: MT | Medicines Authority | Identifier(s): MA1507/02501, MA1507/02502 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W68672001, W68672002, W68672003, W68672004, W68673001, W68673002, W68673003, W68673004 |
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