TYVERB

This brand name is authorized in Austria, Croatia, Cyprus, Estonia, Finland, France, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, Spain, UK.

Active ingredients

The drug TYVERB contains one active pharmaceutical ingredient (API):

1	Lapatinib ditosylate monohydrate UNII G873GX646R - LAPATINIB DITOSYLATE
	Lapatinib, a 4-anilinoquinazoline, is an inhibitor of the intracellular tyrosine kinase domains of both EGFR (ErbB1) and of HER2 (ErbB2) receptors (estimated Kiapp values of 3nM and 13nM, respectively) with a slow off-rate from these receptors (half-life greater than or equal to 300 minutes). Lapatinib inhibits ErbB-driven tumour cell growth in vitro and in various animal models.
	Read more about Lapatinib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
TYVERB Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01EH01	Lapatinib	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors
Discover more medicines within L01EH01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1361089, 1361135, 1484467, 1590757
ES	Centro de información online de medicamentos de la AEMPS	07440005
FI	Lääkealan turvallisuus- ja kehittämiskeskus	384211
FR	Base de données publique des médicaments	65609052
GB	Medicines & Healthcare Products Regulatory Agency	176363, 213030
IE	Health Products Regulatory Authority	88670
IT	Agenzia del Farmaco	038633018, 038633020, 038633032, 038633044, 038633057, 038633069
LT	Valstybinė vaistų kontrolės tarnyba	1033314, 1033315, 1054658, 1063295, 1063296, 1063297, 1067344
NL	Z-Index G-Standaard, PRK	90018
PL	Rejestru Produktów Leczniczych	100141022
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W64592005