TYVERB

This brand name is authorized in Austria, Cyprus, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, United Kingdom

Active ingredients

The drug TYVERB contains one active pharmaceutical ingredient (API):

1 Lapatinib ditosylate monohydrate UNII G873GX646R - LAPATINIB DITOSYLATE

Lapatinib, a 4-anilinoquinazoline, is an inhibitor of the intracellular tyrosine kinase domains of both EGFR (ErbB1) and of HER2 (ErbB2) receptors (estimated Kiapp values of 3nM and 13nM, respectively) with a slow off-rate from these receptors (half-life greater than or equal to 300 minutes). Lapatinib inhibits ErbB-driven tumour cell growth in vitro and in various animal models. Read about Lapatinib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
TYVERB Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EH01	Lapatinib	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors
Discover more medicines within L01EH01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1361089, 1361135, 1484467, 1590757
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 07440005
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 384211
Country: FR	Base de données publique des médicaments	Identifier(s): 65609052
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 176363, 213030
Country: IE	Health Products Regulatory Authority	Identifier(s): 88670
Country: IT	Agenzia del Farmaco	Identifier(s): 038633018, 038633020, 038633032, 038633044, 038633057, 038633069
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1033314, 1033315, 1054658, 1063295, 1063296, 1063297, 1067344
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 90018
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100141022
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W64592005