This brand name is authorized in Austria, Estonia, Spain, France, Croatia, Ireland, Italy, Japan, Lithuania, United States
The drug UPLIZNA contains one active pharmaceutical ingredient (API):
|
1
Inebilizumab
UNII 74T7185BMM - INEBILIZUMAB
|
|
Inebilizumab is a monoclonal antibody that specifically binds to CD19, a cell surface antigen present on pre-B and mature B-cell lymphocytes, including plasmablasts and some plasma cells. Following cell surface binding to B lymphocytes, inebilizumab supports antibody-dependent cellular cytolysis (ADCC) and antibody-dependent cellular phagocytosis (ADCP). B cells are believed to play a central role in the pathogenesis of NMOSD. The precise mechanism by which inebilizumab exerts its therapeutic effects in NMOSD is unknown. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| UPLIZNA Concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC | |
| UPLIZNA Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L04AG10 | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AG Monoclonal antibodies | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1836547, 1881806 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1211602001 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 60878038 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 050085012 |
| Country: JP | 医薬品医療機器総合機構 | Identifier(s): 6399429A1026 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1094784 |
| Country: US | FDA, National Drug Code | Identifier(s): 72677-551 |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
