UPTRAVI

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug UPTRAVI contains one active pharmaceutical ingredient (API):

1 Selexipag UNII 5EXC0E384L - SELEXIPAG

Selexipag is a selective IP receptor agonist distinct from prostacyclin and its analogues. Selexipag is hydrolysed by carboxylesterases to yield its active metabolite, which is approximately 37-fold more potent than selexipag. Stimulation of the IP receptor by selexipag and the active metabolite leads to vasodilatory as well as anti-proliferative and anti-fibrotic effects. Read about Selexipag

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
UPTRAVI Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
B01AC27		B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin
Discover more medicines within B01AC27

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 12235Y, 12240F, 12241G, 12242H, 12245L, 12246M, 12247N, 12248P, 12249Q, 12251T, 12252W, 12253X, 12257D, 12258E, 12259F, 12260G, 12263K, 12264L, 12265M, 12266N
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 514519120034617, 514519120034717, 514519120034817, 514519120034917, 514519120035017, 514519120035117, 514519120035217, 514519120035317, 514519120035417
Country: CA	Health Products and Food Branch	Identifier(s): 02451158, 02451166, 02451174, 02451182, 02451190, 02451204, 02451212, 02451220
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 5210-MEE-0720, 5211-MEE-0720, 5212-MEE-0720, 5213-MEE-0720, 5217-MEE-0720, 5218-MEE-0720, 5219-MEE-0720, 5220-MEE-0720
Country: EE	Ravimiamet	Identifier(s): 1718962, 1718973, 1718984, 1719008, 1719019, 1719020, 1719031, 1719042, 1719053, 1719064
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1151083002, 1151083004, 1151083005, 1151083006, 1151083007, 1151083008, 1151083009, 1151083010
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 035514, 076740, 080632, 158281, 390548, 463311, 484594, 562401, 598861
Country: FR	Base de données publique des médicaments	Identifier(s): 61050007, 61387896, 62611475, 63092880, 63817001, 64003920, 66157358, 67667620
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 329637, 329639, 329643, 329647, 329651, 329655, 329659, 329663, 329676
Country: HK	Department of Health Drug Office	Identifier(s): 65584, 65585, 65586, 65587, 65588, 65589, 65590, 65591
Country: IE	Health Products Regulatory Authority	Identifier(s): 88975, 88976, 88977, 88978, 88979, 88980, 88981, 88982, 88983
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8030, 8031, 8032, 8033, 8034, 8035, 8036, 8037, 8038
Country: IT	Agenzia del Farmaco	Identifier(s): 044887014, 044887026, 044887038, 044887040, 044887053, 044887065, 044887077, 044887089, 044887091, 044887103, 044887115
Country: JP	医薬品医療機器総合機構	Identifier(s): 2190037F1020, 2190037F2027
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1080382, 1080383, 1080384, 1080385, 1080386, 1080387, 1080388, 1080389, 1080390, 1080391, 1083721
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 134260, 134279, 134287, 134295, 134309, 134317, 134325, 134333
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 17455, 17456, 17457, 17458, 17459, 17460, 17461, 17465
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100372187, 100372201, 100372218, 100372224, 100372247, 100372253, 100372260, 100372276
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W67358001, W67358002, W67358003, W67359001, W67360001, W67361001, W67362001, W67363001, W67364001, W67365001
Country: SG	Health Sciences Authority	Identifier(s): 15283P, 15284P, 15285P, 15286P, 15287P, 15288P, 15289P, 15290P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699593095498, 8699593095504, 8699593095511, 8699593095528, 8699593095535, 8699593095542, 8699593095559, 8699593095566, 8699593095573
Country: US	FDA, National Drug Code	Identifier(s): 66215-602, 66215-604, 66215-606, 66215-608, 66215-610, 66215-612, 66215-614, 66215-616
Country: ZA	Health Products Regulatory Authority	Identifier(s): 53/7.1.3/0631, 53/7.1.3/0632, 53/7.1.3/0633, 53/7.1.3/0634, 53/7.1.3/0635, 53/7.1.3/0636, 53/7.1.3/0637, 53/7.1.3/0638