UPTRAVI

This brand name is authorized in United States. It is also authorized in Australia, Austria, Brazil, Canada, Croatia, Cyprus, Ecuador, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, South Africa, Spain, Turkey, UK.

Active ingredients

The drug UPTRAVI contains one active pharmaceutical ingredient (API):

1	Selexipag UNII 5EXC0E384L - SELEXIPAG
	Selexipag is a selective IP receptor agonist distinct from prostacyclin and its analogues. Selexipag is hydrolysed by carboxylesterases to yield its active metabolite, which is approximately 37-fold more potent than selexipag. Stimulation of the IP receptor by selexipag and the active metabolite leads to vasodilatory as well as anti-proliferative and anti-fibrotic effects.
	Read more about Selexipag

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
UPTRAVI Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
B01AC27		B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin
Discover more medicines within B01AC27

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	12235Y, 12240F, 12241G, 12242H, 12245L, 12246M, 12247N, 12248P, 12249Q, 12251T, 12252W, 12253X, 12257D, 12258E, 12259F, 12260G, 12263K, 12264L, 12265M, 12266N
BR	Câmara de Regulação do Mercado de Medicamentos	514519120034617, 514519120034717, 514519120034817, 514519120034917, 514519120035017, 514519120035117, 514519120035217, 514519120035317, 514519120035417
CA	Health Products and Food Branch	02451158, 02451166, 02451174, 02451182, 02451190, 02451204, 02451212, 02451220
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	5210-MEE-0720, 5211-MEE-0720, 5212-MEE-0720, 5213-MEE-0720, 5217-MEE-0720, 5218-MEE-0720, 5219-MEE-0720, 5220-MEE-0720
EE	Ravimiamet	1718962, 1718973, 1718984, 1719008, 1719019, 1719020, 1719031, 1719042, 1719053, 1719064
ES	Centro de información online de medicamentos de la AEMPS	1151083002, 1151083004, 1151083005, 1151083006, 1151083007, 1151083008, 1151083009, 1151083010
FI	Lääkealan turvallisuus- ja kehittämiskeskus	035514, 076740, 080632, 158281, 390548, 463311, 484594, 562401, 598861
FR	Base de données publique des médicaments	61050007, 61387896, 62611475, 63092880, 63817001, 64003920, 66157358, 67667620
GB	Medicines & Healthcare Products Regulatory Agency	329637, 329639, 329643, 329647, 329651, 329655, 329659, 329663, 329676
HK	Department of Health Drug Office	65584, 65585, 65586, 65587, 65588, 65589, 65590, 65591
IE	Health Products Regulatory Authority	88975, 88976, 88977, 88978, 88979, 88980, 88981, 88982, 88983
IL	מִשְׂרַד הַבְּרִיאוּת	8030, 8031, 8032, 8033, 8034, 8035, 8036, 8037, 8038
IT	Agenzia del Farmaco	044887014, 044887026, 044887038, 044887040, 044887053, 044887065, 044887077, 044887089, 044887091, 044887103, 044887115
JP	医薬品医療機器総合機構	2190037F1020, 2190037F2027
LT	Valstybinė vaistų kontrolės tarnyba	1080382, 1080383, 1080384, 1080385, 1080386, 1080387, 1080388, 1080389, 1080390, 1080391, 1083721
NL	Z-Index G-Standaard, PRK	134260, 134279, 134287, 134295, 134309, 134317, 134325, 134333
NZ	Medicines and Medical Devices Safety Authority	17455, 17456, 17457, 17458, 17459, 17460, 17461, 17465
PL	Rejestru Produktów Leczniczych	100372187, 100372201, 100372218, 100372224, 100372247, 100372253, 100372260, 100372276
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W67358001, W67358002, W67358003, W67359001, W67360001, W67361001, W67362001, W67363001, W67364001, W67365001
SG	Health Sciences Authority	15283P, 15284P, 15285P, 15286P, 15287P, 15288P, 15289P, 15290P
TR	İlaç ve Tıbbi Cihaz Kurumu	8699593095498, 8699593095504, 8699593095511, 8699593095528, 8699593095535, 8699593095542, 8699593095559, 8699593095566, 8699593095573
US	FDA, National Drug Code	66215-602, 66215-604, 66215-606, 66215-608, 66215-610, 66215-612, 66215-614, 66215-616
ZA	Health Products Regulatory Authority	53/7.1.3/0631, 53/7.1.3/0632, 53/7.1.3/0633, 53/7.1.3/0634, 53/7.1.3/0635, 53/7.1.3/0636, 53/7.1.3/0637, 53/7.1.3/0638