This brand name is authorized in United States
The drug VABOMERE contains a combination of these active pharmaceutical ingredients (APIs):
1
Vaborbactam
UNII 1C75676F8V - VABORBACTAM
|
Vaborbactam is a non-beta-lactam inhibitor of class A and class C serine beta-lactamases, including Klebsiella pneumoniae carbapenemase, KPC. It acts by forming a covalent adduct with beta-lactamases and is stable to beta-lactamase-mediated hydrolysis. Vaborbactam does not inhibit class B enzymes (metallo-β-lactamases) or class D carbapenemases. Vaborbactam has no antibacterial activity. |
2
Meropenem
UNII FV9J3JU8B1 - MEROPENEM
|
Meropenem exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in Gram-positive and Gram-negative bacteria through binding to penicillin-binding proteins (PBPs). |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: US | FDA, National Drug Code | Identifier(s): 70842-120 |
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