This brand name is authorized in United States. It is also authorized in Austria, Canada, Croatia, Estonia, France, Ireland, Italy, Lithuania, Spain.
The drug VELSIPITY contains one active pharmaceutical ingredient (API):
1
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UNII
6WH8495MMH - ETRASIMOD
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Etrasimod is a sphingosine-1-phosphate (S1P) receptor modulator that binds to S1P receptors 1, 4 and 5 (S1P1,4,5) and is a balanced G-protein and beta-arrestin agonist at S1P1. Etrasimod has minimal activity on S1P3 and no activity on S1P2. Etrasimod partially and reversibly blocks the capacity of lymphocytes to egress from lymphoid organs, reducing the number of lymphocytes in peripheral blood thereby lowering the number of activated lymphocytes in the tissue. The mechanism by which etrasimod exerts therapeutic effects in ulcerative colitis is unknown but may involve the reduction of lymphocyte migration into sites of inflammation. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| VELSIPITY Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| VELSIPITY Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| L04AE05 | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AE Sphingosine-1-phosphate (S1P) receptor modulators | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| CA | Health Products and Food Branch | 02544903 |
| EE | Ravimiamet | 3063585, 3063596, 3063608 |
| ES | Centro de información online de medicamentos de la AEMPS | 1231790001 |
| FR | Base de données publique des médicaments | 62832598 |
| IT | Agenzia del Farmaco | 051115018, 051115020, 051115032 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1099032, 1099033, 1099034 |
| US | FDA, National Drug Code | 0069-0274, 63539-274 |
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