VENCLYXTO

This brand name is authorized in Austria, Croatia, Cyprus, Estonia, Finland, France, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, Spain, Tunisia, Turkey, UK.

Active ingredients

The drug VENCLYXTO contains one active pharmaceutical ingredient (API):

1	Venetoclax UNII N54AIC43PW - VENETOCLAX
	Venetoclax is a potent, selective inhibitor of B-cell lymphoma (BCL)-2, an anti-apoptotic protein. Overexpression of BCL-2 has been demonstrated in CLL and AML cells where it mediates tumour cell survival and has been associated with resistance to chemotherapeutics. Venetoclax binds directly to the BH3-binding groove of BCL-2, displacing BH3 motif-containing pro-apoptotic proteins like BIM, to initiate mitochondrial outer membrane permeabilization (MOMP), caspase activation, and programmed cell death.
	Read more about Venetoclax

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
VENCLYXTO Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01XX52		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX52

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1734386, 1734397, 1734409, 1734410, 1734421, 1734432, 1734443
ES	Centro de información online de medicamentos de la AEMPS	161138002, 161138004, 161138005
FI	Lääkealan turvallisuus- ja kehittämiskeskus	104541, 108133, 137028, 599982
FR	Base de données publique des médicaments	62598280, 63696471, 64449755
GB	Medicines & Healthcare Products Regulatory Agency	337594, 337595, 337596, 337598, 337600
IE	Health Products Regulatory Authority	88970, 88971, 88972, 88973, 88974
IT	Agenzia del Farmaco	045198013, 045198025, 045198037, 045198049, 045198052, 045198064, 045198076
LT	Valstybinė vaistų kontrolės tarnyba	1081759, 1081760, 1081761, 1081762, 1081763, 1081764, 1081765
NL	Z-Index G-Standaard, PRK	138231, 138258, 138266
PL	Rejestru Produktów Leczniczych	100381861, 100381878, 100381884
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W64703001, W64704001, W64705001, W64705002, W64705003
TN	Direction de la Pharmacie et du Médicament	16913041H, 16913042H, 16913043H, 16913044H, 1691345H
TR	İlaç ve Tıbbi Cihaz Kurumu	8680656080438, 8680656080445, 8680656080452, 8680656080469, 8680656080476, 8680656080483, 8680656080490