VERZENIO

This brand name is authorized in Australia, Canada, Ecuador, Hong Kong, Israel, Japan, Singapore, United States, South Africa

Active ingredients

The drug VERZENIO contains one active pharmaceutical ingredient (API):

1 Abemaciclib UNII 60UAB198HK - ABEMACICLIB

Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4 and CDK6), and most active against Cyclin D1/CDK4 in enzymatic assays. Abemaciclib prevents retinoblastoma protein (Rb) phosphorylation, blocking cell cycle progression from the G1 to the S-phase of cell division, leading to suppression of tumour growth. Read about Abemaciclib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VERZENIOS Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EF03		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EF Cyclin-dependent kinase (CDK) inhibitors
Discover more medicines within L01EF03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 11868P, 11871T, 11876C
Country: CA	Health Products and Food Branch	Identifier(s): 02487098, 02487101, 02487128, 02487136
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 5330-MEE-0720, 5435-MEE-0820, 5549-MEE-1020
Country: HK	Department of Health Drug Office	Identifier(s): 66494, 66495, 66496
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8334, 8335, 8336
Country: JP	医薬品医療機器総合機構	Identifier(s): 4291054F1026, 4291054F2022, 4291054F3029
Country: SG	Health Sciences Authority	Identifier(s): 15788P, 15789P, 15790P
Country: US	FDA, National Drug Code	Identifier(s): 0002-4483, 0002-4815, 0002-5337, 0002-6216
Country: ZA	Health Products Regulatory Authority	Identifier(s): 53/26/0434, 53/26/0435, 53/26/0436, 53/26/0437