VERZENIOS

This brand name is authorized in Austria, Brazil, Cyprus, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, United Kingdom

Active ingredients

The drug VERZENIOS contains one active pharmaceutical ingredient (API):

1 Abemaciclib UNII 60UAB198HK - ABEMACICLIB

Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4 and CDK6), and most active against Cyclin D1/CDK4 in enzymatic assays. Abemaciclib prevents retinoblastoma protein (Rb) phosphorylation, blocking cell cycle progression from the G1 to the S-phase of cell division, leading to suppression of tumour growth. Read about Abemaciclib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VERZENIOS Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EF03		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EF Cyclin-dependent kinase (CDK) inhibitors
Discover more medicines within L01EF03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 507619060021902, 507619060022002, 507619060022102, 507619060022202, 507619060022302, 507619060022402, 507619060022502, 507619060022602
Country: EE	Ravimiamet	Identifier(s): 1780657, 1780668, 1780679, 1780680, 1780691, 1780703, 1780815, 1780826, 1780837, 1804261, 1804272, 1804283, 1804294, 1804306, 1804317, 1804328, 1804339, 1804340
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1181307011, 1181307013, 1181307015
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 047163, 082977, 099402, 165790, 375994, 492851
Country: FR	Base de données publique des médicaments	Identifier(s): 64453084, 67160229, 67393660
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 361118, 361120, 361131, 361133, 361146, 361147, 392557, 392559, 392917
Country: IT	Agenzia del Farmaco	Identifier(s): 047091018, 047091020, 047091032, 047091044, 047091057, 047091069, 047091071, 047091083, 047091095, 047091107, 047091119, 047091121, 047091133, 047091145, 047091158, 047091160, 047091172, 047091184, 047091196, 047091208, 047091210
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1086410, 1086411, 1086412, 1086413, 1086414, 1086415, 1086416, 1086417, 1086418, 1086584, 1086585, 1086586, 1086587, 1086588, 1086589, 1086955, 1086956, 1086957, 1086958, 1086959, 1086960
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100413064, 100413070, 100413093
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W65264001, W65265001, W65266001