VOXZOGO

This brand name is authorized in Austria, Estonia, Spain, France, Croatia, Ireland, Italy, Japan, Lithuania, Poland, Romania

Active ingredients

The drug VOXZOGO contains one active pharmaceutical ingredient (API):

1 Vosoritide UNII 7SE5582Q2P - VOSORITIDE

Vosoritide is a modified type C natriuretic peptide (CNP). In patients with achondroplasia, endochondral bone growth is negatively regulated due to a gain of function mutation in fibroblast growth factor receptor 3 (FGFR3). Binding of vosoritide to natriuretic peptide receptor-B (NPR-B) antagonises FGFR3 downstream signalling. As a result, vosoritide, like CNP, acts as a positive regulator of endochondral bone growth as it promotes chondrocyte proliferation and differentiation. Read about Vosoritide

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VOXZOGO Powder and solvent for solution for injection	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
M05BX07		M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BX Other drugs affecting bone structure and mineralization
Discover more medicines within M05BX07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1861152, 1861163, 1861174
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1211577001, 1211577002, 1211577003
Country: FR	Base de données publique des médicaments	Identifier(s): 60787186, 64530919, 68092884
Country: IT	Agenzia del Farmaco	Identifier(s): 049692015, 049692027, 049692039
Country: JP	医薬品医療機器総合機構	Identifier(s): 3999465D1028, 3999465D2024, 3999465D3020
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1093281, 1093282, 1093283
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100457685, 100457692, 100457712
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W68898001, W68899001, W68900001