This brand name is authorized in Austria, Estonia, Finland, France, Ireland, Italy, Lithuania, Netherlands, Poland, United Kingdom
The drug XALUPRINE contains one active pharmaceutical ingredient (API):
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1
Mercaptopurine monohydrate
UNII E7WED276I5 - MERCAPTOPURINE
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Mercaptopurine is an inactive pro-drug which acts as a purine antagonist but requires cellular uptake and intracellular anabolism to thioguanine nucleotides for cytotoxicity. The mercaptopurine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. The thioguanine nucleotides are also incorporated into nucleic acids and this contributes to the cytotoxic effects of the active substance. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| XALUPRINE Oral suspension | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01BB02 | Mercaptopurine | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1558920 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 164324 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 63798857 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 219703 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 43350 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 044665014 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1065399 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 103748 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100313569 |
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