This brand name is authorized in Austria, Canada, Croatia, Estonia, Finland, France, Ireland, Israel, Italy, Lithuania, Poland, Spain, UK.
The drug YESCARTA contains one active pharmaceutical ingredient (API):
1
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UNII
U2I8T43Y7R - AXICABTAGENE CILOLEUCEL
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Axicabtagene ciloleucel, an engineered autologous T-cell immunotherapy product, binds to CD19 expressing cancer cells and normal B cells. Following anti-CD19 CAR T-cell engagement with CD19 expressing target cells, a sequence of events leads to apoptosis and necrosis of CD19-expressing target cells. Αxicabtagene ciloleucel is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) and primary mediastinal large B-cell lymphoma (PMBCL), after two or more lines of systemic therapy. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| YESCARTA Dispersion for infusion | MPI, EU: SmPC | European Medicines Agency (EU) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| L01X | Other antineoplastic agents | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents |
| L01XL03 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XL Antineoplastic cell and gene therapy | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| CA | Health Products and Food Branch | 02485648 |
| EE | Ravimiamet | 1778597 |
| ES | Centro de información online de medicamentos de la AEMPS | 1181299001 |
| FI | Lääkealan turvallisuus- ja kehittämiskeskus | 402302 |
| FR | Base de données publique des médicaments | 63887327 |
| GB | Medicines & Healthcare Products Regulatory Agency | 364610 |
| IL | מִשְׂרַד הַבְּרִיאוּת | 8696 |
| IT | Agenzia del Farmaco | 046995015 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1086198 |
| PL | Rejestru Produktów Leczniczych | 100410634 |
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