This brand name is authorized in Austria, Canada, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Italy, Lithuania, Poland, United Kingdom
The drug YESCARTA contains one active pharmaceutical ingredient (API):
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Axicabtagene ciloleucel
UNII U2I8T43Y7R - AXICABTAGENE CILOLEUCEL
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Axicabtagene ciloleucel, an engineered autologous T-cell immunotherapy product, binds to CD19 expressing cancer cells and normal B cells. Following anti-CD19 CAR T-cell engagement with CD19 expressing target cells, a sequence of events leads to apoptosis and necrosis of CD19-expressing target cells. Αxicabtagene ciloleucel is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) and primary mediastinal large B-cell lymphoma (PMBCL), after two or more lines of systemic therapy. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| YESCARTA Dispersion for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01X | Other antineoplastic agents | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents |
| L01XL03 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XL Antineoplastic cell and gene therapy | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02485648 |
| Country: EE | Ravimiamet | Identifier(s): 1778597 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1181299001 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 402302 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 63887327 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 364610 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 8696 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 046995015 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1086198 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100410634 |
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