ICD-10 Specific code C38.8: Malignant neoplasm: Overlapping lesion of heart, mediastinum and pleura

Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.

Translations

Language Translation
Flag for English language  English Malignant neoplasm: Overlapping lesion of heart, mediastinum and pleura
Flag for French language  French Tumeur maligne ร  localisations contiguรซs du coeur, du mรฉdiastin et de la plรจvre

Hierarchical position

Level Code Title
1 II Neoplasms
2 C00-C97 Malignant neoplasms
3 C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
4 C38 Malignant neoplasm of heart, mediastinum and pleura
5 C38.8 Malignant neoplasm: Overlapping lesion of heart, mediastinum and pleura

Indicated medicines

Active Ingredient Description
Ifosfamide

Ifosfamide is an antineoplastic, a cytotoxic alkylating agent. It is a prodrug and shows no in vitro cytotoxic activity until activated by microsomal enzymes. The cytotoxic activity of ifosfamide (alkylation of the nucleophilic centres in the cells) is associated with the activated oxazaphosphorine ring hydroxylated at the C4 atom which interacts with DNA-DNA cross linking. This activity manifests itself by blocking the late S and early G2 phases of the cell cycle.