Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
| Language | Translation |
|---|---|
English
|
Malignant neoplasm: Long bones of lower limb |
French
|
Tumeur maligne des os longs du membre inférieur |
| Level | Code | Title | |
|---|---|---|---|
| 1 | II | Neoplasms | |
| 2 | C00-C97 | Malignant neoplasms | |
| 3 | C40-C41 | Malignant neoplasms of bone and articular cartilage | |
| 4 | C40 | Malignant neoplasm of bone and articular cartilage of limbs | |
| 5 | C40.2 | Malignant neoplasm: Long bones of lower limb |
| Active Ingredient | Description | |
|---|---|---|
| Ifosfamide |
Ifosfamide is an antineoplastic, a cytotoxic alkylating agent. It is a prodrug and shows no in vitro cytotoxic activity until activated by microsomal enzymes. The cytotoxic activity of ifosfamide (alkylation of the nucleophilic centres in the cells) is associated with the activated oxazaphosphorine ring hydroxylated at the C4 atom which interacts with DNA-DNA cross linking. This activity manifests itself by blocking the late S and early G2 phases of the cell cycle. |
