Refractory invasive fungal infections (IFI)

Active Ingredient: Posaconazole

Indication for Posaconazole

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

800 mg in 4 divided doses daily

Route of admnistration

Oral

Defined daily dose

800 - 800 mg

Dosage regimen

From 200 To 200 mg 4 time(s) per day every day

Detailed description

200 mg four times a day. Alternatively, patients who can tolerate food or a nutritional supplement may take 400 mg twice a day during or immediately following a meal or nutritional supplement.

Duration of therapy should be based on the severity of the underlying disease, recovery from immunosuppression, and clinical response.

Dosage considerations

Each dose of posaconazole should be administered during or immediately after a meal, or a nutritional supplement in patients who cannot tolerate food to enhance the oral absorption and to ensure adequate exposure.

800 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

800 - 800 mg

Dosage regimen

From 400 To 400 mg 2 time(s) per day every day

Detailed description

200 mg four times a day. Alternatively, patients who can tolerate food or a nutritional supplement may take 400 mg twice a day during or immediately following a meal or nutritional supplement.

Duration of therapy should be based on the severity of the underlying disease, recovery from immunosuppression, and clinical response.

Dosage considerations

Each dose of posaconazole should be administered during or immediately after a meal, or a nutritional supplement in patients who cannot tolerate food to enhance the oral absorption and to ensure adequate exposure.

Active ingredient

Posaconazole

Posaconazole inhibits the enzyme lanosterol 14α-demethylase (CYP51), which catalyses an essential step in ergosterol biosynthesis.

Read more about Posaconazole

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