Active Ingredient: Deferoxamine
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intramuscular, 500 milligrams deferoxamine, one dose.
The deferoxamine test for iron overload is based on the principle that normal subjects do not excrete more than a fraction of a milligram of iron in their urine daily, and that a standard intramuscular injection of 500 mg of deferoxamine will not increase this above 1 mg (18 micro mol). In iron storage diseases, however, the increase may be well over 1.5 mg (27 micro mol). It should be borne in mind that the test only yields reliable results when renal function is normal.
Deferoxamine is administered as 500 mg intramuscular injection. Urine is then collected for a period of 6 hours and its iron content determined.
Excretion of 1-1.5 mg (18-27 micro mol) of iron during this 6-hour period is suggestive of iron overload; values greater than 1.5 mg (27 micro mol) can be regarded as pathological.
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