Anxiety

Active Ingredient: Alprazolam

Indication for Alprazolam

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Alprazolam is indicated for short-term symptomatic treatment of anxiety in adults. Alprazolam is only indicated when the disorder is severe, disabling or subjecting the individual to extreme distress.

For this indication, competent medicine agencies globally authorize below treatments:

0.25-0.5 mg 3 times daily

For:

Dosage regimens

Oral, between 0.25 milligrams alprazolam and 0.5 milligrams alprazolam, 3 times daily.

Detailed description

Duration of treatment

Alprazolam should be used in the lowest possible effective dose, for the shortest possible time and for a maximum of 2-4 weeks. The need for continued treatment should be reassessed frequently. Long-term treatment is not recommended. The risk of dependence may increase with dose and duration of treatment.

Anxiety

250 micrograms (0.25 mg) to 500 micrograms (0.5 mg) three times daily, increasing if required to a total of 3 mg daily.

In the presence of debilitating disease: 250 micrograms (0.25 mg) two to three times daily to be gradually increased if needed and tolerated.

If side-effects occur, the dose should be lowered. It is advisable to review treatment regularly and to discontinue use as soon as possible. Should longer term treatment be necessary, then intermittent treatment may be considered to minimize the risk of dependence.

The optimum dosage of alprazolam should be based upon the severity of the symptoms and individual patient response. The lowest dose which can control symptoms should be used. Dosage should be reassessed frequently. The usual dosage is stated above; in the few patients who require higher doses, the dosage should be increased cautiously to avoid adverse effects. When higher dosage is required, the evening dose should be increased before the daytime doses. In general, patients who have not previously received psychotropic medications will require lower doses than those so treated, or those with a history of chronic alcoholism.

The dose must be gradually reduced to avoid withdrawal symptoms.

0.25 mg 3 times daily

For:

Dosage regimens

Oral, 0.25 milligrams alprazolam, 3 times daily.

Detailed description

Duration of treatment

Alprazolam should be used in the lowest possible effective dose, for the shortest possible time and for a maximum of 2-4 weeks. The need for continued treatment should be reassessed frequently. Long-term treatment is not recommended. The risk of dependence may increase with dose and duration of treatment.

Anxiety

250 micrograms (0.25 mg) two to three times daily to be gradually increased if needed and tolerated.

If side-effects occur, the dose should be lowered. It is advisable to review treatment regularly and to discontinue use as soon as possible. Should longer term treatment be necessary, then intermittent treatment may be considered to minimize the risk of dependence.

The optimum dosage of alprazolam should be based upon the severity of the symptoms and individual patient response. The lowest dose which can control symptoms should be used. Dosage should be reassessed frequently. The usual dosage is stated above; in the few patients who require higher doses, the dosage should be increased cautiously to avoid adverse effects. When higher dosage is required, the evening dose should be increased before the daytime doses. In general, patients who have not previously received psychotropic medications will require lower doses than those so treated, or those with a history of chronic alcoholism.

The dose must be gradually reduced to avoid withdrawal symptoms.

Active ingredient

Alprazolam

Alprazolam, like other benzodiazepines, has a high affinity for the benzodiazepine binding site in the brain. It facilitates the inhibitory neurotransmitter action of gamma-aminobutyric acid, which mediates both pre- and post synaptic inhibition in the central nervous system (CNS).

Read more about Alprazolam

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