Drug-related extrapyramidal symptoms

Active Ingredient: Biperiden

Indication for Biperiden

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

2.5-20 mg daily

Route of admnistration

Intramuscular

Defined daily dose

2.5 - 20 mg

Dosage regimen

From 0.625 To 5 mg 4 time(s) per day every day

Loading dose

2.5 mg

Detailed description

Inject 2.5-5 mg biperiden as a single dose intramuscularly or slowly intravenously. If necessary, the same dose can be injected again after 30 minutes. The maximum daily dose amounts to 10–20 mg biperiden.

1-2mg 2–3 times daily

Route of admnistration

Oral

Defined daily dose

2 - 6 mg

Dosage regimen

From 0.667 To 2 mg 3 time(s) per day every day

Detailed description

For the treatment of drug-related extrapyramidal symptoms, 1-2mg is administered 2–3 times daily concomitantly with the neuroleptic (corresponding to 2–6 mg biperiden hydrochloride/day), depending on the severity of the symptoms.

Dosage considerations

Should be taken with sufficient liquid preferably during or after a meal.

2.5-20 mg daily

Route of admnistration

Intravenous

Defined daily dose

2.5 - 20 mg

Dosage regimen

From 0.625 To 5 mg 4 time(s) per day every day

Loading dose

2.5 mg

Detailed description

Inject 2.5-5 mg biperiden as a single dose intramuscularly or slowly intravenously. If necessary, the same dose can be injected again after 30 minutes. The maximum daily dose amounts to 10–20 mg biperiden.

Active ingredient

Biperiden

Biperiden is a predominantly centrally acting anti-cholinergic. It has a peripheral effect, which is low in comparison to atropine. Biperiden binds competitively to peripheral and central muscarinic receptors (primarily M1).

Read more about Biperiden

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