Active Ingredient: Zuranolone
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 50 milligrams zuranolone, once daily to dinner, over the duration of 14 days.
The recommended dosage of zuranolone is 50 mg taken orally once daily in the evening for 14 days. If patients experience CNS depressant effects within the 14-day period, consider reducing the dosage to 40 mg once daily in the evening within the 14-day period.
Zuranolone can be used alone or as an adjunct to oral antidepressant therapy.
The safety and effectiveness of zuranolone use beyond 14 days in a single treatment course have not been established.
If a zuranolone evening dose is missed, take the next dose at the regular time the following evening. Do not take extra capsules on the same day to make up for the missed dose. Continue taking zuranolone once daily until the remainder of the 14-day treatment course is completed.
Administer zuranolone with fat-containing food (e.g., 400 to 1,000 calories, 25% to 50% fat).
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