Active Ingredient: Etanercept
Treatment of active and progressive psoriatic arthritis in adults when the response to previous diseasemodifying antirheumatic drug therapy has been inadequate. Etanercept has been shown to improve physical function in patients with psoriatic arthritis, and to reduce the rate of progression of peripheral joint damage as measured by X-ray in patients with polyarticular symmetrical subtypes of the disease.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A: Subcutaneous, 25 milligrams etanercept, 2 times weekly.
Regimen B: Subcutaneous, 50 milligrams etanercept, once weekly.
25 mg etanercept administered twice weekly is the recommended dose. Alternatively, 50 mg administered once weekly has been shown to be safe and effective.
Available data suggest that a clinical response is usually achieved within 12 weeks of treatment. Continued therapy should be carefully reconsidered in a patient not responding within this time period.
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