Active Ingredient: Human hepatitis B immunoglobulin
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous
2,000 - 10,000 [iU]
From 2,000 To 10,000 [iU] once every day for 7 day(s)
10,000 [iU]
2,000 [iU]
10 000 IU on the day of transplantation, peri-operatively, then 2000-10 000 IU (40-200 ml)/day for 7 days, and as necessary to maintain antibody levels above 100-150 IU/l in HBV-DNA negative patients and above 500 IU/l in HBV-DNA positive patients.
Human hepatitis B immunoglobulin solution should be infused intravenously at an initial rate of 0.1 ml/kg/hr for 10 minutes. In case of adverse reaction, either the rate of administration must be reduced or the infusion stopped. If well tolerated, the rate of administration may gradually be increased to a maximum of 1 ml/kg/hr.
For:
Intravenous
10,000 - 10,000 [iU] per m² of body surface area (BSA)
From 10,000 To 10,000 [iU] per m² of body surface area (BSA) once every day
Posology should be adjusted according to body surface area, on the basis of 10000 IU/1.73 m².
Human hepatitis B immunoglobulin solution should be infused intravenously at an initial rate of 0.1 ml/kg/hr for 10 minutes. In case of adverse reaction, either the rate of administration must be reduced or the infusion stopped. If well tolerated, the rate of administration may gradually be increased to a maximum of 1 ml/kg/hr.
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