Active Ingredient: Ixekizumab
Ixekizumab is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 160 milligrams ixekizumab, 1 one dose, over the duration of 2 weeks. Afterwards, subcutaneous, 80 milligrams ixekizumab, once every 2 weeks, 6 doses in total, over the duration of 14 weeks. Afterwards, subcutaneous, 80 milligrams ixekizumab, once every 4 weeks.
The recommended dose is 160 mg by subcutaneous injection at Week 0, followed by 80 mg at Weeks 2, 4, 6, 8, 10, and 12, then maintenance dosing of 80 mg every 4 weeks.
Consideration should be given to discontinuing treatment in patients who have shown no response after 16 to 20 weeks of treatment. Some patients with initially partial response may subsequently improve with continued treatment beyond 20 weeks.
No dose adjustment is required in subjects aged ≥65 years. There is limited information in subjects aged ≥75 years.
If possible, areas of the skin that show psoriasis should be avoided as injection sites.
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