Terminal illness

Active Ingredient: Levomepromazine

Indication for Levomepromazine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Levomepromazine is a neuroleptic with indications in psychiatry and general medicine, particularly in terminal illness. Clinically it is more sedative and more potent than chlorpromazine in the management of psychotic conditions and in the relief of severe chronic pain.

For this indication, competent medicine agencies globally authorize below treatments:

12.5-37.5 mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

12.5 - 37.5 mg

Dosage regimen

From 4.167 To 12.5 mg 3 time(s) per day every day

Detailed description

Children are very susceptible to the hypotensive and soporific effects of levomepromazine. It is advised that a total daily oral dosage of 75 mg should not be exceeded.

0.35-3 mg/kg in 3 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

0.35 - 3 mg per kg of body weight

Dosage regimen

From 0.117 To 1 mg per kg of body weight 3 time(s) per day every day

Detailed description

Clinical experience with parenteral levomepromazine in children is limited. Where indicated, doses of 0.35 mg/kg/day to 3.0 mg/kg/day are recommended.

0.35-3 mg/kg in 3 divided doses daily

Route of admnistration

Intramuscular

Defined daily dose

0.35 - 3 mg per kg of body weight

Dosage regimen

From 0.117 To 1 mg per kg of body weight 3 time(s) per day every day

Detailed description

Clinical experience with parenteral levomepromazine in children is limited. Where indicated, doses of 0.35 mg/kg/day to 3.0 mg/kg/day are recommended.

Active ingredient

Levomepromazine

Levomepromazine resembles chlorpromazine and promethazine in the pattern of its pharmacology. It possesses anti-emetic, antihistamine and anti-adrenaline activity and exhibits a strong sedative effect.

Read more about Levomepromazine

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