Breast cancer

Active Ingredient: Doxorubicin

Indication for Doxorubicin

Population group: only adults (18 years old or older)

Doxorubicin is indicated as monotherapy for patients with metastatic breast cancer, where there is an increased cardiac risk.

For this indication, competent medicine agencies globally authorize below treatments:

50 mg/m² once every 4 weeks

Route of admnistration

Intravenous

Defined daily dose

50 - 50 mg per m² of body surface area (BSA)

Dosage regimen

From 50 To 50 mg per m² of body surface area (BSA) once every 28 day(s)

Detailed description

Doxorubicin is administered intravenously at a dose of 50 mg/m² once every 4 weeks for as long as the disease does not progress and the patient continues to tolerate treatment.

Dosage considerations

To minimise the risk of infusion reactions, the initial dose is administered at a rate no greater than 1 mg/minute. If no infusion reaction is observed, subsequent doxorubicin infusions may be administered over a 60-minute period.

Active ingredient

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic obtained from Streptomyces peucetius var. caesius. The exact mechanism of the antitumour activity of doxorubicin is not known. It is generally believed that inhibition of DNA, RNA and protein synthesis is responsible for the majority of the cytotoxic effects.

Read more about Doxorubicin

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.