Arrhythmias

Active Ingredient: Propranolol

Indication for Propranolol

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

40-160 mg in 4 divided doses daily

Route of admnistration

Oral

Defined daily dose

40 - 160 mg

Dosage regimen

From 10 To 40 mg 4 time(s) per day every day

Loading dose

40 mg

Detailed description

Most patients respond within the dosage range of 10-40 mg three or four times daily.

1-10 mg

Route of admnistration

Intravenous

Defined daily dose

1 - 10 mg

Dosage regimen

From 1 To 10 mg once every day

Detailed description

The initial dose is 1 mg given over 1 minute. The dose may be repeated at 2 minute intervals until a response is achieved or up to a maximum dose of 10 mg in conscious patients or 5 mg in anesthetized patients.

Active ingredient

Propranolol

Propranolol is a competitive antagonist at both beta, and beta2-adrenoceptor, but has membrane stabilising activity at concentrations exceeding 1-3mg/litre, though such concentrations are rarely achieved during oral therapy. Competitive beta-blockade has been demonstrated in man by a parallel shift to the right in the dose-heart rate response curve to beta-agonists such as isoprenaline.

Read more about Propranolol

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