Mucopolysaccharidosis type II

Active Ingredient: Idursulfase

Indication for Idursulfase

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Idursulfase is indicated for the long-term treatment of patients with Hunter syndrome (Mucopolysaccharidosis II, MPS II).

For this indication, competent medicine agencies globally authorize below treatments:

0.5 mg/kg once every week

Route of admnistration

Intravenous

Defined daily dose

0.5 - 0.5 mg per kg of body weight

Dosage regimen

From 0.5 To 0.5 mg per kg of body weight once every 7 day(s)

Detailed description

Idursulfase is administered at a dose of 0.5 mg/kg body weight every week by intravenous infusion over a 3 hour period, which may be gradually reduced to 1 hour if no infusion-associated reactions are observed.

Active ingredient

Idursulfase

Idursulfase (idursulfase) is a purified form of the lysosomal enzyme iduronate-2-sulfatase, produced in a human cell line providing a human glycosylation profile, which is analogous to the naturally occurring enzyme. Elaprase is indicated for the long-term treatment of patients with Hunter syndrome (Mucopolysaccharidosis II, MPS II).

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