Active Ingredient: Tetanus immunoglobulin
Immediate prophylaxis after tetanus prone injuries in patients not adequately vaccinated, in patients whose immunisation status is not known with certainty, and in patients with severe deficiency in antibody production or vaccinated patients with high risk wounds.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intramuscular, between 250 international units tetanus immunoglobulin and 500 international units tetanus immunoglobulin, daily, one dose.
Prophylaxis of tetanus prone wounds:
If a large volume (>2 ml for children or >5 ml for adults) is required, it is recommended to administer this in divided doses at different sites.
When simultaneous vaccination is necessary, the immunoglobulin and the vaccine should be administered at two different sites.
For prophylaxis, if intramuscular administration is contraindicated (bleeding disorders), the injection can be administered subcutaneously. However, it should be noted that there are no clinical efficacy data to support administration by the subcutaneous route.
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