Acute gout

Active Ingredient: Colchicine

Indication for Colchicine

Population group: only adults (18 years old or older)

Treatment of acute gout.

For this indication, competent medicine agencies globally authorize below treatments:

1.5mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

1.5 - 1.5 mg

Dosage regimen

From 0.5 To 0.5 mg 3 time(s) per day every day for 4 day(s)

Detailed description

1 mg to start followed by 500 micrograms after 1 hour. No further tablets should be taken for 12 hours. After 12 hours, treatment can resume if necessary with a maximum dose of 500 micrograms every 8 hours until symptoms are relieved.

The course of treatment should end when symptoms are relieved or when a total of 6 mg has been taken. No more than 6 mg should be taken as a course of treatment. After completion of a course, another course should not be started for at least 3 days (72 hours).

Active ingredient

Colchicine

Colchicine is considered to act against the inflammatory response to urate crystals, by possibly inhibiting the migration of granulocytes into the inflamed area. Other properties of colchicine, such as interaction with the microtubules, could also contribute to the operation. Onset of action is approximately 12 hours after oral administration and is maximal after 1 to 2 days.

Read more about Colchicine

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