Schizoaffective disorder

Active Ingredient: Haloperidol

Indication for Haloperidol

Population group: only adults (18 - 65 years old)

For this indication, competent medicine agencies globally authorize below treatments:

2-20 mg in 1-2 divided doses daily

Route of admnistration

Oral

Defined daily dose

2 - 20 mg

Dosage regimen

From 1 To 10 mg 2 time(s) per day every day

Loading dose

2 mg

Detailed description

  • 2 to 10 mg/day orally, as a single dose or in 2 divided doses. Patients with first-episode schizophrenia generally respond to 2 to 4 mg/day, whereas patients with multiple-episode schizophrenia may need doses up to 10 mg/day.
  • Adjustments to the dose may be made every 1 to 7 days.
  • Doses above 10 mg/day have not demonstrated superior efficacy to lower doses in the majority of patients and may cause an increased incidence of extrapyramidal symptoms. The individual benefit-risk should be assessed when considering doses above 10 mg/day.
  • The maximum dose is 20 mg/day because safety concerns outweigh the clinical benefits of treatment at higher doses.

Treatment withdrawal

Gradual withdrawal of haloperidol is advisable.

Missed dose

If patients miss a dose, it is recommended that they take the next dose as usual, and do not take a double dose.

Active ingredient

Haloperidol

Haloperidol is an antipsychotic belonging to the butyrophenones group. It is a potent central dopamine type 2 receptor antagonist, and at recommended doses, has low alpha-1 antiadrenergic activity and no antihistaminergic or anticholinergic activity.

Read more about Haloperidol

Related medicines

Summary of Product Characteristics (SPC) 2017: HALOPERIDOL Solution for injection
Summary of Product Characteristics (SPC) 2017: HALOPERIDOL Oral solution
Structured Product Labeling (SPL) 2020: HALDOL DECANOATE Solution for injection

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