Migraine

Active Ingredient: Galcanezumab

Indication for Galcanezumab

Galcanezumab is indicated for the prophylaxis of migraine in adults who have at least 4 migraine days per month.

For this indication, competent medicine agencies globally authorize below treatments:

120-240 mg once monthly

Route of admnistration

Subcutaneous

Defined daily dose

120 - 240 mg

Dosage regimen

From 120 To 240 mg once every 30 day(s)

Loading dose

240 mg

Maintenance dose

120 mg

Detailed description

The recommended dose is 120 mg galcanezumab injected subcutaneously once monthly, with a 240 mg loading dose as the initial dose.

Patients should be instructed to inject a missed dose as soon as possible and then resume monthly dosing.

The treatment benefit should be assessed within 3 months after initiation of treatment. Any further decision to continue treatment should be taken on an individual patient basis. Evaluation of the need to continue treatment is recommended regularly thereafter.

Dosage considerations

Galcanezumab is to be injected subcutaneously in the abdomen, thigh, back of the upper arm, or in the gluteal region.

Active ingredient

Galcanezumab

Galcanezumab is a humanised IgG4 monoclonal antibody that binds calcitonin gene-related peptide (CGRP) thus preventing its biological activity. Elevated blood concentrations of CGRP have been associated with migraine attacks.

Read more about Galcanezumab

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