Active Ingredient: Interferon, alfa-2b
For this indication, competent medicine agencies globally authorize below treatments:
Subcutaneous
2,000,000 - 2,000,000 [iU] per m² of body surface area (BSA)
From 2,000,000 To 2,000,000 [iU] per m² of body surface area (BSA) once every 2 day(s)
The recommended dose is 2 million IU/m² administered subcutaneously three times a week (every other day) for both splenectomised and non-splenectomised patients. For most patients with hairy cell leukaemia, normalisation of one or more haematological variables occurs within one to two months of interferon alpha-2b treatment. Improvement in all three haematological variables (granulocyte count, platelet count and haemoglobin level) may require six months or more. This regimen must be maintained unless the disease progresses rapidly or severe intolerance is manifested.
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