Duodenal ulcer, benign gastric ulcer

Active Ingredient: Ranitidine

Indication for Ranitidine

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

150-200 mg in 3-4 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

150 - 200 mg

Dosage regimen

From 37.5 To 50 mg 4 time(s) per day every day

Detailed description

Ranitidine may be given either as a slow (over 2 minutes) intravenous injection up to a maximum of 50 mg, after dilution to a volume of 20 ml per 50 mg dose, which may be repeated every 6 to 8 hours; or as an intermittent intravenous infusion at a rate of 25 mg per hour for two hours; the infusion may be repeated at 6 to 8 hour intervals.

300 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

300 - 300 mg

Dosage regimen

From 150 To 150 mg 2 time(s) per day every day

Detailed description

The standard dosage regimen is 150 mg twice daily or 300 mg at night. It is not necessary to time the dose in relation to meals.

In most cases of duodenal ulcer, benign gastric ulcer and post-operative ulcer, healing occurs within 4 weeks. Healing usually occurs after a further 4 weeks of treatment in those not fully healed after the initial course of therapy.

300 mg once daily

Route of admnistration

Oral

Defined daily dose

300 - 300 mg

Dosage regimen

From 300 To 300 mg once every day

Detailed description

The standard dosage regimen is 150 mg twice daily or 300 mg at night. It is not necessary to time the dose in relation to meals.

In most cases of duodenal ulcer, benign gastric ulcer and post-operative ulcer, healing occurs within 4 weeks. Healing usually occurs after a further 4 weeks of treatment in those not fully healed after the initial course of therapy.

150-200 mg in 3-4 divided doses daily

Route of admnistration

Intramuscular

Defined daily dose

150 - 200 mg

Dosage regimen

From 37.5 To 50 mg 4 time(s) per day every day

Detailed description

Ranitidine may be given either as a slow (over 2 minutes) intravenous injection up to a maximum of 50 mg, after dilution to a volume of 20 ml per 50 mg dose, which may be repeated every 6 to 8 hours; or as an intermittent intravenous infusion at a rate of 25 mg per hour for two hours; the infusion may be repeated at 6 to 8 hour intervals, or as an intramuscular injection of 50 mg (2 ml) every 6 to 8 hours.

Active ingredient

Ranitidine

Ranitidine is a specific rapidly acting histamine H2-antagonist. It inhibits basal and stimulated secretion of gastric acid, reducing both the volume and the acid and pepsin content of the secretion. Ranitidine has a relatively long duration of action and so a single 150 mg dose effectively suppresses gastric acid secretion for twelve hours.

Read more about Ranitidine

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