Active Ingredient: Vismodegib
Vismodegib is indicated for the treatment of adult patients with:
For this indication, competent medicine agencies globally authorize below treatments:
Oral
150 - 150 mg
From 150 To 150 mg once every day
The recommended dose is 150 mg once daily.
If a dose is missed, patients should be instructed not to take the missed dose but to resume with the next scheduled dose.
In clinical trials, treatment with vismodegib was continued until disease progression or until unacceptable toxicity. Treatment interruptions of up to 4 weeks were allowed based on individual tolerability.
Benefit of continued treatment should be regularly assessed, with the optimal duration of therapy varying for each individual patient.
It should be taken with water, with or without food.
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