Endometriosis

Active Ingredient: Leuprorelin

Indication for Leuprorelin

Population group: women, only adolescents (12 years - 18 years old) , adults (18 years old or older)

Management of endometriosis, including pain relief and reduction of endometriotic lesions.

For this indication, competent medicine agencies globally authorize below treatments:

11.25 mg once every 3 month

Route of admnistration

Intramuscular

Defined daily dose

11.25 - 11.25 mg

Dosage regimen

From 11.25 To 11.25 mg once every 90 day(s) for 180 day(s)

Detailed description

The recommended dose is 11.25 mg administered as a single intramuscular injection every 3 months for a period of 6 months only. Treatment should be initiated during the first 5 days of the menstrual cycle.

In women receiving GnRH analogues for the treatment of endometriosis, the addition of hormone replacement therapy (HRT-an estrogen and progestogen) has been shown to reduce bone mineral density loss and vasomotor symptoms.

Therefore if appropriate, HRT should be co-administered with leuprorelin3 taking into account the risks and benefits of each treatment.

3.75 mg once every month

Route of admnistration

Subcutaneous

Defined daily dose

3.75 - 3.75 mg

Dosage regimen

From 3.75 To 3.75 mg once every 30 day(s) for 180 day(s)

3.75 mg once every month

Route of admnistration

Intramuscular

Defined daily dose

3.75 - 3.75 mg

Dosage regimen

From 3.75 To 3.75 mg once every 30 day(s) for 180 day(s)

Active ingredient

Leuprorelin

Leuprorelin is inactive when given orally due to poor membrane permeability and an almost complete inactivation by intestinal proteolytic enzymes. Leuprorelin has potent LHRH agonist properties when given during short-term and intermittent therapy, however, when administered in a continuous, nonpulsatile manner, LHRH analogs induce inhibition of gonadotropin secretion and suppression of testicular steroidogenesis.

Read more about Leuprorelin

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.