Suppression of physiological lactation

Active Ingredient: Cabergoline

Indication for Cabergoline

Population group: women, only adults (18 - 65 years old)

Cabergoline is indicated for suppression of already established lactation:

  1. After parturition, when the mother elects not to breast feed the infant or when breast feeding is contraindicated due to medical reasons related to the mother or the new-born.
  2. After stillbirth or abortion.

Cabergoline suppresses physiological lactation by inhibiting prolactin secretion.

Suppression of milk secretion and relief of breast engorgement and pain are obtained in approximately 85% of nursing women treated with a total dose of 1 mg cabergoline given in four divided doses over two days. Rebound breast symptomatology after day 10 is uncommon (approximately 2% of cases).

For this indication, competent medicine agencies globally authorize below treatments:

0.25 mg every 12 hours for two days

For:

Dosage regimens

Oral, 0.25 milligrams cabergoline, once every 12 hours, over the duration of 2 days.

Detailed description

For suppression of established lactation the recommended therapeutic dosage regimen is 0.25 mg every 12 hours for two days (1 mg total dose). This dosage regimen has been demonstrated to be better tolerated than the single dose regimen in women electing to suppress lactation having a lower incidence of adverse events, in particular of hypotensive symptoms.

Active ingredient

Cabergoline

Cabergoline is a dopaminergic ergoline derivative endowed with a potent and long-lasting PRL-lowering activity.

Read more about Cabergoline

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