Waldendstorm's macroglobulinaemia

Active Ingredient: Chlorambucil

Indication for Chlorambucil

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

2-12 mg once daily

Route of admnistration

Oral

Defined daily dose

2 - 12 mg

Dosage regimen

From 2 To 12 mg once every day

Detailed description

Chlorambucil is one of the treatment choices in this indication.

Starting doses of 6-12 mg daily until leukopenia occurs are recommended followed by 2-8 mg daily indefinitely.

Dosage considerations

Chlorambucil is administered orally and should be taken daily on an empty stomach (at least one hour before meals or three hours after meals).

Active ingredient

Chlorambucil

Chlorambucil is an aromatic nitrogen mustard derivative which acts as a bifunctional alkylating agent. In addition to interference with DNA replication, chlorambucil induces cellular apoptosis via the accumulation of cytosolic p53 and subsequent activation of an apoptosis promoter.

Read more about Chlorambucil

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