Active Ingredient: Isoniazid
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
200 - 300 mg
From 200 To 300 mg once every day
The usual intramuscular or intravenous dose for adults is 200 to 300 mg as a single daily dose, for children 100 to 300 mg daily (10-20 mg/kg), but doses much larger than these are sometimes given, especially in conditions such as tuberculous meningitis. It is recommended to give an intravenous dose slowly as an undiluted bolus injection, although other methods may be employed.
No dosage reduction is necessary in the elderly.
Intramuscular
200 - 300 mg
From 200 To 300 mg once every day
The usual intramuscular or intravenous dose for adults is 200 to 300 mg as a single daily dose, for children 100 to 300 mg daily (10-20 mg/kg), but doses much larger than these are sometimes given, especially in conditions such as tuberculous meningitis. It is recommended to give an intravenous dose slowly as an undiluted bolus injection, although other methods may be employed.
No dosage reduction is necessary in the elderly.
Intrapleural
50 - 250 mg
From 50 To 250 mg once every day
50 to 250 mg may be instilled intrapleurally after aspiration of pus, the dosage of oral isoniazid on that day being correspondingly reduced. The ampoule solution is also used for the local treatment of tuberculous ulcers, for irrigation of fistulae, etc.
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