Influenza

Active Ingredient: Oseltamivir

Indication for Oseltamivir

Population group: only children (1 year - 12 years old)

Oseltamivir is indicated in adults and children including full term neonates who present with symptoms typical of influenza, when influenza virus is circulating in the community. Efficacy has been demonstrated when treatment is initiated within two days of first onset of symptoms.

For this indication, competent medicine agencies globally authorize below treatments:

60-150 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

60 - 150 mg

Dosage regimen

From 30 To 75 mg 2 time(s) per day every day for 5 day(s)

Detailed description

The following weight-adjusted dosing regimens are recommended for treatment of infants and children 1 year of age or older:

Body WeightRecommended dose for 5 days
10 kg to 15 kg30 mg twice daily
>15 kg to 23 kg45 mg twice daily
>23 kg to 40 kg60 mg twice daily
>40 kg75 mg twice daily

Treatment should be initiated as soon as possible within the first two days of onset of symptoms of influenza.

Active ingredient

Oseltamivir

Oseltamivir (oseltamivir carboxylate) is a selective inhibitor of influenza virus neuraminidase enzymes, which are glycoproteins found on the virion surface. Viral neuraminidase enzyme activity is important both for viral entry into uninfected cells and for the release of recently formed virus particles from infected cells, and for the further spread of infectious virus in the body.

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