Active Ingredient: Eculizumab
Eculizumab is indicated in adults and children for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in patients who are anti-aquaporin-4 (AQP4) antibody-positive with a relapsing course of the disease.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
900 - 1,200 mg
From 900 To 1,200 mg once every 7 day(s)
900 mg
1,200 mg
The aHUS, refractory gMG and NMOSD dosing regimen for adult patients (≥18 years of age) consists of a 4 week initial phase followed by a maintenance phase:
The diluted solution of eculizumab should be administered by intravenous infusion over 25–45 minutes (35 minutes ± 10 minutes) in adults.
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