Active Ingredient: Triptorelin
Treatment of confirmed central precocious puberty (girls under 9 years, boys under 10 years).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, between 1.88 milligrams triptorelin and 3.75 milligrams triptorelin, once every 2 weeks, over the duration of 4 weeks. Afterwards, subcutaneous, between 1.88 milligrams triptorelin and 3.75 milligrams triptorelin, once every 3 to 4 weeks.
Dosing at the beginning of treatment should be based on body weight, one injection of triptorelin should be injected on days 0, 14, and 28. Thereafter one injection every 4 weeks. Should the effect be insufficient, the injections may be given every 3 weeks. Dosing should be based on body weight according to the table.
| Body weight | Dosing |
|---|---|
| <20 kg | 1.875 mg (half dose) |
| 20-30 kg | 2.5 mg (2/3 dose) |
| >30 kg | 3.75 mg (full dose) |
The dosage is injected every 28 days either subcutaneously (e.g. into the skin of the abdomen, the buttock or thigh) or deep intramuscularly. The injection site should be changed each time.
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