Central precocious puberty

Active Ingredient: Triptorelin

Indication for Triptorelin

Population group: only children (1 year - 12 years old)
Therapeutic intent: Curative procedure

Treatment of confirmed central precocious puberty (girls under 9 years, boys under 10 years).

For this indication, competent medicine agencies globally authorize below treatments:

1.875-3.75 mg once every 3-4 weeks

For:

Dosage regimens

Subcutaneous, between 1.88 milligrams triptorelin and 3.75 milligrams triptorelin, once every 2 weeks, over the duration of 4 weeks. Afterwards, subcutaneous, between 1.88 milligrams triptorelin and 3.75 milligrams triptorelin, once every 3 to 4 weeks.

Detailed description

Dosing at the beginning of treatment should be based on body weight, one injection of triptorelin should be injected on days 0, 14, and 28. Thereafter one injection every 4 weeks. Should the effect be insufficient, the injections may be given every 3 weeks. Dosing should be based on body weight according to the table.

Body weightDosing
<20 kg1.875 mg (half dose)
20-30 kg2.5 mg (2/3 dose)
>30 kg3.75 mg (full dose)

Dosage considerations

The dosage is injected every 28 days either subcutaneously (e.g. into the skin of the abdomen, the buttock or thigh) or deep intramuscularly. The injection site should be changed each time.

Active ingredient

Triptorelin

Triptorelin is a decapeptide analogue of GnRH which initially stimulates release of pituitary gonadotropins.

Read more about Triptorelin

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